Granzyme B (GZMB) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4E4]
Specifications
| Product Data | |
| Clone Name | OTI4E4 |
|---|---|
| Application | ELISA (indirect), IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 25.5 kDa |
| Gene Name | granzyme B |
| Database Link | |
| Background | Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. provided by RefSeq, Jul 2008 |
| Synonyms | C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT |
| Reference Data | |
| Protein Categories | ADC Targets, Cytokines, Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI4E4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505931 | Carrier-free (BSA/glycerol-free) GZMB mouse monoclonal antibody, clone OTI4E4 (formerly 4E4) | 100 ug |
$620.00
|
|
| TA505931 | GZMB (Granzyme B) mouse monoclonal antibody, clone OTI4E4 (formerly 4E4) | 100 ul |
$447.00
|
|
| TA505931AM | GZMB mouse monoclonal antibody,clone 4E4, Biotinylated | 100 ul |
$509.00
|
|
| TA505931S | GZMB (Granzyme B) mouse monoclonal antibody, clone OTI4E4 (formerly 4E4) | 30 ul |
$200.00
|
|
Citations
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