COPS6 Mouse Monoclonal Antibody [Clone ID: OTI4E7]

CAT#: TA505897

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COPS6 mouse monoclonal antibody, clone OTI4E7 (formerly 4E7)



Special Offer: Try sample size of this antibody at $99/€99. Use code "TrueSample".

USD 447.00


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Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI4E7
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 58-327 of human COPS6(NP_006824) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 36 kDa
Gene Name COP9 signalosome subunit 6
Background The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
Synonyms CSN6; MOV34-34KD
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
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