Cytochrome P450 2A6 (CYP2A6) Mouse Monoclonal Antibody [Clone ID: OTI1D2]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1D2 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150, FLOW 1:100 |
| Reactivity | Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CYP2A6(NP_000753) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1.3 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 56.3 kDa |
| Gene Name | cytochrome P450 family 2 subfamily A member 6 |
| Database Link | |
| Background | This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. provided by RefSeq, Jul 2008 |
| Synonyms | CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI1D2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF503857 | Carrier-free (BSA/glycerol-free) CYP2A6 mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) | 100 ug |
$620.00
|
|
| TA503857AM | CYP2A6 mouse monoclonal antibody,clone 1D2, Biotinylated | 100 ul |
$509.00
|
|
| TA503857BM | CYP2A6 mouse monoclonal antibody,clone 1D2, HRP conjugated | 100 ul |
$509.00
|
|
| TA503857S | CYP2A6 (Cytochrome P450 2A6) mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) | 30 ul |
$200.00
|
|
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