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Estrogen Receptor 1 (ESR1) Mouse Monoclonal Antibody [Clone ID: OTI1B1]

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SKU
TA503759
ESR1 (Estrogen Receptor 1/ER) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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Frequently Bought Together (3)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY400046 Transient overexpression lysate of estrogen receptor 1 (ESR1), transcript variant 1 (as WB positive control) 100 ug
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TP313277 Recombinant protein of human estrogen receptor 1 (ESR1), transcript variant 1, 20 µg
20 ug
$867.00

View other "Estrogen Receptor 1 or NM_000125" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1B1
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ESR1(NP_000116) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 66 kDa
Gene Name estrogen receptor 1
Database Link
Background This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. provided by RefSeq, Jul 2008
Synonyms ER; Era; ESR; ESRA; ESTRR; NR3A1
Reference Data
Protein Categories Cancer: Gynecologic, Cardiovascular diseases, Endocrine and metabolic diseases, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
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Other "OTI1B1" antibodies (5)
SKU Description Size Price
CF503759 Carrier-free (BSA/glycerol-free) ESR1 mouse monoclonal antibody, clone OTI1B1 (formerly 1B1) 100 ug
$620.00
TA503759AM ESR1 (Estrogen Receptor 1/ER) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1), Biotinylated 100 ul
$509.00
TA503759BM ESR1 (Estrogen Receptor 1/ER) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1), HRP conjugated 100 ul
$509.00
TA503759S ESR1 (Estrogen Receptor 1/ER) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1) 30 ul
$200.00
TA700546 purified ESR1 biotinylated mouse monoclonal detection antibody, validated for Luminex assays 50 ug
$494.00

file-alt Citations

Gestational exposure to bisphenol AF causes endocrine disorder of corpus luteum by altering ovarian SIRT-1/Nrf2/NF-kB expressions and macrophage proangiogenic function in mice
Lu, Liu, Liu et al
Biochem Pharmacol (2023) 220, 115954 DOI: 10.1016/j.bcp.2023.115954
Cited by 23
AI Summary: In this study, the OriGene ERα antibody (TA503759S) was used to assess protein expression changes in mouse ovaries, contributing to the analysis of how gestational exposure to bisphenol AF disrupts ovarian endocrine function.
Snippet: ab46154), HIF1a (1:500, Cell Signaling Technology, USA, 36169S), CYP19a1 (1:500, Affinity, China, #BF8059) and ERα (1:1000, OriGene, USA, TA503759S), COX-2 (1:500, Proteintech, China, 66351–1-IG), BCL-2 (1:1000, Signalway Antibody, USA, 40639), BAX (1:1000, Cell Signaling Technology, USA, 14796S),
WB
Clinicopathological Characteristics of Pseudomyxoma Peritonei Originated from Ovaries
Yan, Shi, Li et al
Cancer Manag Res (2020) 12, 7569-7578 DOI: 10.2147/CMAR.S264474
AI Summary: OriGene products, specifically anti-SATB2 antibody (TA806083) and anti-Villin antibody (TA500492), were used for immunohistochemical staining to help characterize and differentiate ovarian-origin pseudomyxoma peritonei tumors in this study.
FigureFigureFigure
Functional role of RRS1 in breast cancer cell proliferation
Song, Ma, Hua et al
J. Cell. Mol. Med. (2018)
AI Summary: OriGene products, specifically primary antibodies against p53, ER, PR, HER2, and Ki67, were used for immunohistochemistry and Western blot analyses to assess protein expression levels in the study of RRS1’s role in breast cancer cell proliferation.
Snippet: Primary antibodies were used against the following targets: RRS1 (1: 1000;Abcam, Cambridgeshire, UK), p53 (1: 300;OriGene, Shanghai, China), ER (1: 300;OriGene), PR (1: 300;OriGene), HER2 (1: 300;Ori- Gene) and Ki67 (1: 300;OriGene)
IHC WB IP
Prediction model of lymphovascular invasion based on clinicopathological factors in Chinese patients with invasive breast cancer
Shen, Wu, Xiao et al
Medicine (Baltimore) (2018) 97 (43), e12973 DOI: 10.1097/MD.0000000000012973
Cited by 18
AI Summary: OriGene products, specifically the anti-HER-2 antibody (TA808229), anti-Ki67 antibody (TA500294), and anti-P53 antibody (TA802901), were used for immunohistochemical detection of protein expression in breast cancer tissue samples, contributing to the evaluation of clinicopathological risk factors for lymphovascular invasion in this study.
FigureFigureFigure
Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor
Andreani, Bartolacci, Wijnant et al
Aging (Albany NY) (2017) 9 (2), 508-523 DOI: 10.18632/aging.101175
AI Summary: OriGene’s mouse monoclonal anti-ERα antibody was used for Western blot analysis to assess ERα protein levels in the study investigating resveratrol’s effects on HER2+/ERα+ breast cancer.
Snippet: ER α mouse monoclonal anti-ER α WB 1:1000 ORIGENE PCNA rabbit monoclonal anti-PCNA IHC 1:200 Dako
WB IHC
Significance of estrogen receptor subtypes in breast tumorigenesis and progression
Sun, Gu, Xia et al
Tumour Biol (2014) 35 (9), 9111-7 DOI: 10.1007/s13277-014-2152-1
Cited by 5
Showing 1-6 of 6 papers.
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