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EIF4E Mouse Monoclonal Antibody [Clone ID: OTI6C3]

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SKU
TA502896
EIF4E mouse monoclonal antibody, clone OTI6C3 (formerly 6C3)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "EIF4E or NM_001968" antibodies

Specifications
Specifications
Product Data
Clone Name OTI6C3
Application FC, IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human EIF4E (NP_001959) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.52 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 24.9 kDa
Gene Name eukaryotic translation initiation factor 4E
Database Link
Background All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 PubMed 3469651). supplied by OMIM
Synonyms AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways Insulin signaling pathway, mTOR signaling pathway
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Other "OTI6C3" antibodies (4)
SKU Description Size Price
CF502896 Carrier-free (BSA/glycerol-free) EIF4E mouse monoclonal antibody, clone OTI6C3 (formerly 6C3) 100 ug
$620.00
TA502896AM EIF4E mouse monoclonal antibody, clone OTI6C3 (formerly 6C3), Biotinylated 100 ul
$509.00
TA502896BM EIF4E mouse monoclonal antibody, clone OTI6C3 (formerly 6C3), HRP conjugated 100 ul
$509.00
TA502896S EIF4E mouse monoclonal antibody, clone OTI6C3 (formerly 6C3) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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