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VASP Mouse Monoclonal Antibody [Clone ID: OTI4D6]

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SKU
TA502647S
VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
In Stock*
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View other "VASP or NM_003370" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4D6
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000
Simple Western 1:100
IHC 1:150
IF 1:100
FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human VASP(NP_003361) produced in 293T Cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 39.6 kDa
Gene Name vasodilator stimulated phosphoprotein
Database Link
Background Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. provided by RefSeq
Synonyms vasodilator-stimulated phosphoprotein
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration
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Other "OTI4D6" antibodies (4)
SKU Description Size Price
CF502647 Carrier-free (BSA/glycerol-free) VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6) 100 ug
$620.00
TA502647 VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6) 100 ul
$447.00
TA502647AM VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6), Biotinylated 100 ul
$509.00
TA502647BM VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6), HRP conjugated 100 ul
$509.00

file-alt Citations

Enhanced substrate stress relaxation promotes filopodia-mediated cell migration
Adebowale, Gong, Hou et al
Nat Mater (2021)
Cited by 270
AI Summary: OriGene's anti-VASP antibody (TA502647) was used in this study to detect VASP protein, aiding in the analysis of cell migration mechanisms on substrates with different stress relaxation properties.
Snippet: … These observations result from adherent cell migration studies on stiff, elastic substrates, because most;The following primary antibodies were used: anti-paxillin antibody Y113 (1:500, Abcam ab32084), anti-focal adhesion kinase (1:500, Thermo Fisher 700255), anti-myosin light chain, phosphor-specific S19 (1:250, EMD Millipore AB3381), anti-myosin-X (1:250, Novus Biologicals 22430002) and anti-VASP (1:100, Origene TA502647). …
Showing 1-1 of 1 papers.
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