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VASP Mouse Monoclonal Antibody [Clone ID: OTI4D6]

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SKU
CF502647
Carrier-free (BSA/glycerol-free) VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "VASP or NM_003370" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4D6
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000
Simple Western 1:100
IHC 1:150
IF 1:100
FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human VASP(NP_003361) produced in 293T Cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 39.6 kDa
Gene Name vasodilator stimulated phosphoprotein
Database Link
Background Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. provided by RefSeq
Synonyms vasodilator-stimulated phosphoprotein
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration
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Other "OTI4D6" antibodies (4)
SKU Description Size Price
TA502647 VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6) 100 ul
$447.00
TA502647AM VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6), Biotinylated 100 ul
$509.00
TA502647BM VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6), HRP conjugated 100 ul
$509.00
TA502647S VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6) 30 ul
$200.00

file-alt Citations

Enhanced substrate stress relaxation promotes filopodia-mediated cell migration
Adebowale, Gong, Hou et al
Nat Mater (2021)
Cited by 270
AI Summary: OriGene's anti-VASP antibody (TA502647) was used in this study to detect VASP protein, aiding in the analysis of cell migration mechanisms on substrates with different stress relaxation properties.
Snippet: … These observations result from adherent cell migration studies on stiff, elastic substrates, because most;The following primary antibodies were used: anti-paxillin antibody Y113 (1:500, Abcam ab32084), anti-focal adhesion kinase (1:500, Thermo Fisher 700255), anti-myosin light chain, phosphor-specific S19 (1:250, EMD Millipore AB3381), anti-myosin-X (1:250, Novus Biologicals 22430002) and anti-VASP (1:100, Origene TA502647). …
Showing 1-1 of 1 papers.
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