PKC epsilon (PRKCE) Mouse Monoclonal Antibody [Clone ID: OTI4G8]
Specifications
| Product Data | |
| Clone Name | OTI4G8 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PRKCE (NP_005391) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 83.5 kDa |
| Gene Name | protein kinase C epsilon |
| Database Link | |
| Background | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. provided by RefSeq |
| Synonyms | nPKC-epsilon; PKCE |
| Reference Data | |
| Protein Categories | Cytokines, Enzyme: Kinases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4G8" antibodies (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502415 | Carrier-free (BSA/glycerol-free) PRKCE mouse monoclonal antibody, clone OTI4G8 (formerly 4G8) | 100 ug |
$620.00
|
|
| TA502415 | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI4G8 (formerly 4G8) | 100 ul |
$447.00
|
|
| TA502415AM | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI4G8 (formerly 4G8), Biotinylated | 100 ul |
$509.00
|
|
| TA502415BM | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI4G8 (formerly 4G8), HRP conjugated | 100 ul |
$509.00
|
|
| TA600076 | PRKCE mouse monoclonal capture antibody, validated for ELISA and Luminex assays | 100 ug |
$458.00
|
|
| TA700073 | PRKCE biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays | 50 ug |
$494.00
|
|
Citations
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