CDCP1 Mouse Monoclonal Antibody [Clone ID: OTI2C1]

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SKU
TA502228S
CDCP1 mouse monoclonal antibody, clone OTI2C1 (formerly 2C1)
  $200.00
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Specifications
Specifications
Product Data
Clone Name OTI2C1
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDCP1 (NP_073753) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.58 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 92.8 kDa
Gene Name CUB domain containing protein 1
Database Link
Background The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq
Synonyms CD318; SIMA135; TRASK
Note
  • This antibody also reacts with SNX8 and TRAF1
  • WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families ES Cell Differentiation/IPS, Transmembrane
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Other "OTI2C1" antibodies (4)
SKU Description Size Price
CF502228 Carrier-free (BSA/glycerol-free) CDCP1 mouse monoclonal antibody, clone OTI2C1 (formerly 2C1) 100 ug
$620.00
TA502228 CDCP1 mouse monoclonal antibody, clone OTI2C1 (formerly 2C1) 100 ul
$447.00
TA502228AM CDCP1 mouse monoclonal antibody, clone OTI2C1 (formerly 2C1), Biotinylated 100 ul
$509.00
TA502228BM CDCP1 mouse monoclonal antibody, clone OTI2C1 (formerly 2C1), HRP conjugated 100 ul
$509.00

file-alt Citations

Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas
Gao, Xu, Chen et al
PLoS Biol. (2019) 17 (8), e3000425 DOI: 10.1371/journal.pbio.3000425
AI Summary: OriGene’s anti-CDCP1 monoclonal antibody (TA502228) was used to identify and isolate CDCP1+ cancer stem cells, enabling the study of their role in chemotherapy resistance and tumor recurrence in mutant Kras colorectal carcinomas.
Snippet: l suspension was rinsed with PBS after detaching and centrifuged at 1,100 rpm for 10 min. Pelleted cells were resuspended in PBS with a 1:100 dilution of the anti-CDCP1 monoclonal antibody (TA502228;Origene, Rockville, MD, USA). The cell–antibody complex was incubated at room temperature for 30 min and rinsed twice with PBS. This step was followed by 15 min incubation at 6°C–12°C with a 1:5
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