SAMHD1 Mouse Monoclonal Antibody

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SKU
TA502157
SAMHD1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)
  $447.00
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Specifications
Specifications
Product Data
Application FC, IF, IHC, Simple Western, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100, Simple Western 1:20 - 1:50
Reactivity Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human SAMHD1(NP_056289) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 72 kDa
Background This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. provided by RefSeq
Synonyms CHBL2; DCIP; HDDC1; MOP-5; SBBI88
Reference Data
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Other antibodies (4)
SKU Description Size Price
CF502157 Carrier-free (BSA/glycerol-free) SAMHD1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1) 100 ug
$620.00
TA502157AM SAMHD1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1), Biotinylated 100 ul
$509.00
TA502157BM SAMHD1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1), HRP conjugated 100 ul
$509.00
TA502157S SAMHD1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1) 30 ul
$200.00

file-alt Citations

Azacytidine Induces Global DNA Hypomethylation and Increases Cellular and Nuclear SAMHD1 in Feline Lymphocytes
Bienzle, Asadian
preprints.org (2021)
Snippet: relevant antibodies for 30 min at room temperature (RT) in the dark. The SAMHD1 antibody (clone OTI1A1, OriGene, Rockville, MD) was conjugated to Alexa Fluor 488 and the pSAMHD1 antibody (clone T592p, EMD Millipore
FC
Interferon γ and α Have Differential Effects on SAMHD1, a Potent Antiviral Protein, in Feline Lymphocytes
Asadian, Bienzle
Viruses (2019) 11 (10) DOI: 10.3390/v11100921
AI Summary: OriGene's SAMHD1 antibody (clone OTI1A1) conjugated to Alexa Fluor 488 was used in this study to detect and analyze SAMHD1 protein expression and localization in feline lymphocytes.
Snippet: The SAMHD1 antibody (clone OTI1A1, OriGene, Rockville, MD, USA) conjugated to Alexa Fluor 488, or the pSAMHD1 antibody (clone T592p, EMD Millipore, Billerica, MA, USA) that conjugated to Pacific Blue (Zenon labeling kit, Molecular Probes, Thermo Fisher, Mississauga Cached
FC
Brain microglial cells are highly susceptible to HIV-1 infection and spread
Cenker, Stultz, McDonald
AIDS Res. Hum. Retroviruses (2017)
AI Summary: OriGene's mouse anti-SAMHD1 antibody (Clone 1A1) was used in this study to detect and analyze SAMHD1 protein levels in various macrophage populations, helping to elucidate the role of SAMHD1 in restricting HIV-1 infection.
Snippet: min at room temperature. Cells were stained for SAMHD1 (Clone 1A1, Origene, Rockville, ... nylon membranes and individually probed with the following antibodies: mouse anti- SAMHD1 (Clone 1A1, Origene, Rockville, MD), rabbit anti-phospho-T592 SAMHD1 (Cell ... All 3 versions Cite SaveSaving
WB
Imaging HIV-1 Genomic DNA from Entry through Productive Infection
Stultz, Cenker, McDonald
J. Virol. (2017)
AI Summary: In this study, OriGene's mouse monoclonal anti-SAMHD1 antibody (Clone 1A1) was used to detect and analyze the role of the SAMHD1 restriction factor in HIV-1 infection of monocyte-derived macrophages.
Snippet: Mouse monoclonal antibodies f or HIV-1 p24 CA (Clone 588 AG3.0, NIH AIDS Reagent Program, Germantown, MD), Lamin A/C (Cl one 4C11, 589 on March 4, 2017 by UNIV OF NEWCASTLE http://jvi.asm.org/ Downloaded from Imaging HIV-1 Genomes 28 Sigma-Aldrich, St. Louis, MO), and SAMHD1 (Clone 1A1, Origene, Rockville, MD) were 590 used in this study
IF
Showing 1-4 of 4 papers.
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