FADD Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C11]
Specifications
| Product Data | |
| Clone Name | OTI1C11 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:2000, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 23.1 kDa |
| Gene Name | Fas associated via death domain |
| Database Link | |
| Background | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. provided by RefSeq |
| Synonyms | GIG3; MORT1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Apoptosis, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1C11" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF501434 | Carrier-free (BSA/glycerol-free) FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) | 100 ug |
$620.00
|
|
| TA501434 | Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) | 100 ul |
$447.00
|
|
| TA501434AM | Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11), Biotinylated | 100 ul |
$509.00
|
|
| TA501434S | Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) | 30 ul |
$200.00
|
|
Citations
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