FADD Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C11]

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SKU
TA501434AM
Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11), Biotinylated
  $509.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name OTI1C11
Application FC, WB
Recommended Dilution WB 1:2000, FLOW 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 23.1 kDa
Gene Name Fas associated via death domain
Database Link
Background The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. provided by RefSeq
Synonyms GIG3; MORT1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Alzheimer's disease, Apoptosis, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
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Other "OTI1C11" antibodies (4)
SKU Description Size Price
CF501434 Carrier-free (BSA/glycerol-free) FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 100 ug
$620.00
TA501434 Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 100 ul
$447.00
TA501434BM Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11), HRP conjugated 100 ul
$509.00
TA501434S Anti-FADD mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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