BDH2 Mouse Monoclonal Antibody [Clone ID: OTI4G4]

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SKU
TA501291
Anti-BDH2 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI4G4
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BDH2(NP_064524) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.73 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 26.5 kDa
Gene Name 3-hydroxybutyrate dehydrogenase 2
Database Link
Synonyms DHRS6; EFA6R; PRO20933; SDR15C1; UCPA-OR; UNQ6308
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Butanoate metabolism, Metabolic pathways, Synthesis and degradation of ketone bodies
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Other "OTI4G4" antibodies (4)
SKU Description Size Price
CF501291 Carrier-free (BSA/glycerol-free) BDH2 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 100 ug
$620.00
TA501291AM Anti-BDH2 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4), Biotinylated 100 ul
$509.00
TA501291BM Anti-BDH2 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4), HRP conjugated 100 ul
$509.00
TA501291S Anti-BDH2 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 30 ul
$200.00

file-alt Citations

Inflammation and ER stress downregulate BDH2 expression and dysregulate intracellular iron in macrophages
Zughaier, Stauffer, McCarty
J Immunol Res (2014) 2014, 140728 DOI: 10.1155/2014/140728
Cited by 34
AI Summary: OriGene products contributed to this study by providing the BDH2 antibody (Cat# TA322013) and BDH2 cDNA clone (Cat# RC203307), which were used to detect and manipulate BDH2 expression in macrophages to investigate its regulation under inflammation and ER stress.
FigureFigureFigure
Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy
Chang, Olson, Schwartz
Nutr Metab (Lond) (2013) 10 (1), 47 DOI: 10.1186/1743-7075-10-47
Cited by 105
AI Summary: OriGene’s BDH2 antibody (clone 2G1, TA501293) was used in this study to assess the expression of the ketolytic enzyme BDH2 in malignant glioma tissues via immunohistochemistry, contributing to the evaluation of metabolic enzyme profiles relevant to potential ketogenic diet therapy.
Snippet: cytosolic beta- hydroxybutyrate dehydrogenase (BDH2, clone 2G1, OriGene TA501293, Rockville, MD), and rabbit poly- clonal antibody to acetyl-CoA acetyltransferase (ACAT1, Sigma HPA007569). Immunohistochemistry reactions
FigureFigure
IHC
Showing 1-2 of 2 papers.
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