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RIC8 (RIC8A) Mouse Monoclonal Antibody [Clone ID: OTI3G3]

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SKU
TA501055
Anti-RIC8A (RIC8) mouse monoclonal antibody, clone OTI3G3 (formerly 3G3)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
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View other "RIC8 or NM_021932" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3G3
Application IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RIC8A (NP_068751) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.83 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 59.6 kDa
Gene Name RIC8 guanine nucleotide exchange factor A
Database Link
Background Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation
Synonyms RIC8
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI3G3" antibodies (4)
SKU Description Size Price
CF501055 Carrier-free (BSA/glycerol-free) RIC8A mouse monoclonal antibody, clone OTI3G3 (formerly 3G3) 100 ug
$620.00
TA501055AM Anti-RIC8A (RIC8) mouse monoclonal antibody, clone OTI3G3 (formerly 3G3), Biotinylated 100 ul
$509.00
TA501055BM Anti-RIC8A (RIC8) mouse monoclonal antibody, clone OTI3G3 (formerly 3G3), HRP conjugated 100 ul
$509.00
TA501055S Anti-RIC8A (RIC8) mouse monoclonal antibody, clone OTI3G3 (formerly 3G3) 30 ul
$200.00

file-alt Citations

Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A
Yan, Ha, Dhanasekaran
J Mol Signal (2015) 10, 3 DOI: 10.5334/1750-2187-10-3
Cited by 6
FigureFigureFigure
Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A
Yan, Ha
Journal of Molecular Signaling (2015)
Snippet: For the endogenous protein immunoprecipitation, 1 mg of the total protein lysate was incubated with 1 µg of normal mouse-IgG, Gα 13 (clone 73.1;Santa Cruz Biotechnology, Santa Cruz, CA) or Ric-8A-antibody (clone 3G3, OriGene, Rockville, MD) for 2 hours. ... Cite SaveSaving
IP
Showing 1-2 of 2 papers.
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