BTN3A2 Mouse Monoclonal Antibody [Clone ID: OTI1A6]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1A6 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human BTN3A2 (NP_008978) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 36.4 kDa |
| Gene Name | butyrophilin subfamily 3 member A2 |
| Database Link | |
| Background | This gene encodes a member of the immunoglobulin superfamily, containing two Ig domains with similarity to Ig variable and Ig constant domains. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus on chromosome 6 in the seven member BTN cluster, which includes butyrophilin, and three members each of the BTN2 and BTN3 subfamilies. Alternatively spliced transcript variants have been described but their full-length nature has yet to be determined. |
| Synonyms | BT3.2; BTF4; BTN3.2; CD277 |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI1A6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500730 | Carrier-free (BSA/glycerol-free) BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) | 100 ug |
$620.00
|
|
| TA500730AM | Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), Biotinylated | 100 ul |
$509.00
|
|
| TA500730BM | Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), HRP conjugated | 100 ul |
$509.00
|
|
| TA500730S | Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) | 30 ul |
$200.00
|
|
Citations
Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2
Xu, Yu, Xu et al
bioRxiv (2024)
Xu, Yu, Xu et al
bioRxiv (2024)
Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells
Wang, Henry, Distefano et al
J. Immunol. (2013) 191 (3), 1029-42 DOI: 10.4049/jimmunol.1300658
Wang, Henry, Distefano et al
J. Immunol. (2013) 191 (3), 1029-42 DOI: 10.4049/jimmunol.1300658
Cited by 148
AI Summary: In this study, the OriGene anti-BTN3 (1A6) monoclonal antibody was used to investigate the role of BTN3A1 in the stimulation of human Vγ2Vδ2 T cells by prenyl pyrophosphates.
Snippet: mAbs used included anti-Cδ (anti-TCRδ1 [5A6.E9]), anti-Vγ1 (23D12), anti-Vγ2 (7A5), anti-Vδ1 (δTCS1) (all from Pierce Abs, Thermo Scientific, Rockford, IL), anti-Vδ2 (BB3), anti-Vδ3 (P11.5B), anti-BTN3 (1A6) (OriGene, Rockville, MD), FITC–anti-CD3 (HIT3a) (eBioscience
Showing 1-2 of 2 papers.
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