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BTN3A2 Mouse Monoclonal Antibody [Clone ID: OTI1A6]

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SKU
CF500730
Carrier-free (BSA/glycerol-free) BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "BTN3A2 or NM_007047" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1A6
Application IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BTN3A2 (NP_008978) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 36.4 kDa
Gene Name butyrophilin subfamily 3 member A2
Database Link
Background This gene encodes a member of the immunoglobulin superfamily, containing two Ig domains with similarity to Ig variable and Ig constant domains. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus on chromosome 6 in the seven member BTN cluster, which includes butyrophilin, and three members each of the BTN2 and BTN3 subfamilies. Alternatively spliced transcript variants have been described but their full-length nature has yet to be determined.
Synonyms BT3.2; BTF4; BTN3.2; CD277
Reference Data
Protein Categories Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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Other "OTI1A6" antibodies (4)
SKU Description Size Price
TA500730 Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 100 ul
$447.00
TA500730AM Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), Biotinylated 100 ul
$509.00
TA500730BM Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), HRP conjugated 100 ul
$509.00
TA500730S Anti-BTN3A2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 30 ul
$200.00

file-alt Citations

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2
Xu, Yu, Xu et al
bioRxiv (2024)
Snippet: … SARS-CoV-2 invades;mouse anti-ACE2 (Cell Signaling Technology, USA, #74512, 1:100), mouse anti-GFP (Santa Cruz Biotechnology, USA, #sc-99961:2000), and mouse antiBTN3A2 antibodies (ORIGENE, USA, #CF500730, 1:50), respectively. …
IHC
Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells
Wang, Henry, Distefano et al
J. Immunol. (2013) 191 (3), 1029-42 DOI: 10.4049/jimmunol.1300658
Cited by 148
AI Summary: In this study, the OriGene anti-BTN3 (1A6) monoclonal antibody was used to investigate the role of BTN3A1 in the stimulation of human Vγ2Vδ2 T cells by prenyl pyrophosphates.
Snippet: mAbs used included anti-Cδ (anti-TCRδ1 [5A6.E9]), anti-Vγ1 (23D12), anti-Vγ2 (7A5), anti-Vδ1 (δTCS1) (all from Pierce Abs, Thermo Scientific, Rockford, IL), anti-Vδ2 (BB3), anti-Vδ3 (P11.5B), anti-BTN3 (1A6) (OriGene, Rockville, MD), FITC–anti-CD3 (HIT3a) (eBioscience
Showing 1-2 of 2 papers.
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