OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

ERK2 (MAPK1) Mouse Monoclonal Antibody [Clone ID: OTI6F8]

  • Product Brand Image
Be the first to review this product
SKU
TA500468
Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

Frequently Bought Together (3)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY419132 Transient overexpression lysate of mitogen-activated protein kinase 1 (MAPK1), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP310493 Recombinant protein of human mitogen-activated protein kinase 1 (MAPK1), transcript variant 1, 20 µg
20 ug
$867.00

View other "ERK2 or NM_138957" antibodies

Specifications
Specifications
Product Data
Clone Name OTI6F8
Application FC, IHC, IP, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, FLOW 1:100, IP 2ug/500ul
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAPK1(NP_620407) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 41.4 kDa
Gene Name mitogen-activated protein kinase 1
Database Link
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Synonyms ERK; ERK-2; ERK2; ERT1; MAPK2; NS13; p38; p40; p41; p41mapk; p42-MAPK; P42MAPK; PRKM1; PRKM2
Reference Data
Protein Categories Enzyme: Kinases, Growth Factors, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adherens junction, Alzheimer's disease, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Non-small cell lung cancer, Oocyte meiosis, Pancreatic cancer, Pathways in cancer, Prion diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, TGF-beta signaling pathway, Thyroid cancer, Toll-like receptor signaling pathway, Type II diabetes mellitus, Vascular smooth muscle contraction, VEGF signaling pathway
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "OTI6F8" antibodies (6)
SKU Description Size Price
CF500468 Carrier-free (BSA/glycerol-free) MAPK1 mouse monoclonal antibody, clone OTI6F8 (formerly 6F8) 100 ug
$620.00
TA500468AM Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8), Biotinylated 100 ul
$509.00
TA500468BM Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8), HRP conjugated 100 ul
$509.00
TA500468S Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8) 30 ul
$200.00
TA600063 MAPK1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700063 MAPK1 biotinylated mouse monoclonal detection antibody, validated for Luminex assays 50 ug
$494.00

file-alt Citations

Microcurrent Stimulation Triggers MAPK Signaling and TGF-β1 Release in Fibroblast and Osteoblast-Like Cell Lines
Konstantinou, Zagoriti, Pyriochou et al
Cells (2020) 9 (9) DOI: 10.3390/cells9091924
Cited by 47
AI Summary: In this study, the total-ERK 1/2 antibody from OriGene was used to assess ERK 1/2 protein levels, helping to elucidate the role of MAPK signaling in microcurrent-stimulated wound healing processes.
Snippet: with primary antibodies for the phosphorylated forms of ERK 1/2 (1:2000 in 5% BSA 0.1% PBS-Tween, Cell Signaling, Beverly, MA, USA), p38 (1:1000 in 5% BSA 0.1% PBS-Tween, Cell Signaling) total-ERK 1/2 (1:1000 in 5% BSA 0.1% PBS-Tween, Origene Cached;- with primary antibodies for the phosphorylated forms of ERK 1/2 (1:2000 in 5% BSA 0.1% PBS-Tween, Cell Signaling, Beverly, MA, USA), p38 (1:1000 in 5% BSA 0.1% PBS-Tween, Cell Signaling) total-ERK 1/2 (1:1000 in 5% BSA 0.1% PBS-Tween, Origene Cached
WB
Alteration of Cytoskeleton Morphology and Gene Expression in Human Breast Cancer Cells under Simulated Microgravity
Strube, Infanger, Wehland et al
Cell J (2020) 22 (1), 106-114 DOI: 10.22074/cellj.2020.6537
Cited by 23
AI Summary: OriGene products, specifically rabbit polyclonal antibodies against vimentin, RhoA, Her2, RAB27A, and MAPK1, were used in this study to detect and confirm protein expression changes in human breast cancer cells under simulated microgravity.
Snippet: in blocking reagent with following dilutions: rabbit polyclonal anti-vimentin (1:2000), rabbit polyclonal anti- RhoA (1:500), rabbit polyclonal anti-Her2 (1:1000), rabbit polyclonal anti-RAB27A (1:1000), rabbit polyclonal anti- MAPK1 (1:1000), all obtained from Origene, USA, as
FigureFigureFigure
WB
Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression
Li, Ma, Lv et al
Molecules (2019) 24 (10) DOI: 10.3390/molecules24101957
AI Summary: OriGene products contributed to this study by providing antibodies against NOX4, P38, JNK, OPN, MCP-1, and GAPDH, which were used for immunoblotting and protein expression analysis.
Snippet: 4. Materials and Methods. 4.1. Antibodies and Reagents. The antibodies against NOX4, P38, JNK, OPN, MCP-1, and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) were obtained from OriGene Technologies (Rockville, MD, USA) Cached;
WB IF FC
The Elevated ASK1 Expression Inhibits Proliferation and Invasion in Gastric Cancer HGC-27 Cells
Wan, Shi, Ma et al
Anat Rec (Hoboken) (2018)
AI Summary: OriGene contributed mouse anti-human monoclonal antibodies against ASK1, p-p38, p38, p-JNK, JNK, p-ERK, ERK, and GAPDH, which were used in Western blot experiments to analyze signaling protein expression in the study.
Snippet: min. The primary antibodies (mouse anti- human monoclonal antibody ASK1/p-p38/p38/p-JNK/JNK p-ERK/ERK/GAPDH, ORIGENE) were added into block- ing solution and incubated with the membranes at 4 C overnight. The
WB
A natural antioxidant, tannic acid mitigates iron-overload induced hepatotoxicity in Swiss albino mice through ROS regulation
Basu, Panja, Shendge et al
Environ. Toxicol. (2018)
AI Summary: OriGene Technologies contributed to this study by providing antibodies against PARP, caspase-3, Bax, pERK-1/2, pJNK, p38, and beta-actin, which were used for protein expression analyses to assess the effects of tannic acid on iron-overload induced hepatotoxicity.
Snippet: diphosphate‐ribose) polymerase (PARP), anti‐caspase‐3, anti‐Bcl‐2‐associated X (Bax), anti‐pERK‐1/2 (extracellular signal‐regulated kinase), anti‐pJNK (c‐Jun N‐terminal kinase), anti‐p38, and anti‐beta‐actin antibodies were purchased from OriGene Technologies;diphosphate-ribose) polymerase (PARP), anti-caspase-3, anti-Bcl-2-associated X (Bax), anti-pERK-1/2 (extracellular signal-regulated kinase), anti-pJNK (c-Jun N-terminal kinase), anti-p38, and anti-beta-actin antibodies were purchased from OriGene Technologies
Showing 1-5 of 5 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products