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c-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: OTI3F2]

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SKU
TA500003
c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI3F2 (formerly 3F2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
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View other "c-Myc or NM_002467" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3F2
Application IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human Myc (NP_002458) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 50.4 kDa
Gene Name MYC proto-oncogene, bHLH transcription factor
Database Link
Background c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Haematopoietic and Lymphoid, Cancer: Head and Neck, Cancer: Lung, Cancer: Sarcoma, Cancer: Skin, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway
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Other "OTI3F2" antibodies (6)
SKU Description Size Price
CF500003 Carrier-free (BSA/glycerol-free) c-Myc mouse monoclonal antibody, clone OTI3F2 (formerly 3F2) 100 ug
$620.00
TA500003AM c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI3F2 (formerly 3F2), Biotinylated 100 ul
$509.00
TA500003BM c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI3F2 (formerly 3F2), HRP conjugated 100 ul
$509.00
TA500003S c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI3F2 (formerly 3F2) 30 ul
$200.00
TA600496 purified MYC mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700497 MYC biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

file-alt Citations

Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
Agarwal, Koh, Tardi et al
EBioMedicine (2021) 72, 103617 DOI: 10.1016/j.ebiom.2021.103617
Cited by 8
AI Summary: OriGene’s anti-c-Myc antibody (clone OTI3F2, TA500003) was used in this study to detect and isolate c-Myc-tagged proteins during co-immunoprecipitation experiments, facilitating the investigation of protein interactions involved in podocyte homeostasis.
Snippet: desired proteins in each case. One mg total cell protein was used per IP and isotype control mouse IgG antibody were used along with antibodies against: FLAG (F1804, Sigma;RRID:AB_262044) and c-Myc (Origene, clone OTI3F2, formerly 3F2, TA500003, RRID:AB_2148581). Anti-FLAG M2 affinity (Sigma), anti-c-Myc agarose and protein A/G beads (Pierce, Thermo Fisher Scientific) were used to isolate protein
FigureFigureFigure
IF SPR IP
Showing 1-1 of 1 papers.
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