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Isocitrate dehydrogenase (IDH1) Mouse Monoclonal Antibody [Clone ID: OTI2H9]

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SKU
TA400028
Anti-IDH1 mouse mAb, clone OTI2H9, DyLight488 conjugated
Size:
100 ul
Conjugation:
DyLight 488 Biotin HRP Unconjugated
  $495.00
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View other "Isocitrate dehydrogenase or NM_005896" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2H9
Application FC
Recommended Dilution FC: 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human IDH1 expression vector
Buffer PBS (pH 7.4) containing 0.1% BSA, 50% glycerol and 0.02% NaN₃
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Conjugation DyLight 488
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 46.7 kDa
Gene Name isocitrate dehydrogenase (NADP(+)) 1
Database Link
Background Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Synonyms HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Haematopoietic and Lymphoid, Cardiovascular diseases, Intracellular Proteins
Protein Pathways Citrate cycle (TCA cycle), Glutathione metabolism, Metabolic pathways
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Other "OTI2H9" antibodies (7)
SKU Description Size Price
CF500610 Carrier-free (BSA/glycerol-free) IDH1 mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) 100 ug
$620.00
TA400008 Anti-IDH1 mouse mAb, clone OTI2H9, Biotinylated 100 ul
$495.00
TA400009 Anti-IDH1 mouse mAb, clone OTI2H9, HRP conjugated 100 ul
$495.00
TA500610 Anti-IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) 100 ul
$447.00
TA500610S Anti-IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) 30 ul
$200.00
TA600198 IDH1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700198 IDH1 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

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