CDC40 Rabbit Polyclonal Antibody

SKU TA392848

Cdc40 (S209) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 181-230 of Human Cdc40.
• Specificity: Cdc40 (S209) polyclonal antibody detects endogenous levels of Cdc40 protein.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 65 kDa
• Gene Name: cell division cycle 40
• Database Link:
  O60508
• Background: Cdc40, also known as pre-mRNA-processing factor 17 (PRPF17) or EH-binding protein 3 (EHB3), is a 579 amino acid nuclear protein. Cdc40 is essential for the catalytic step II of the pre-mRNA splicing process, in which Cdc40 associates with the spliceosome C complex. Cdc40 contains seven WD repeats, which are important in protein-protein interactions. Cdc40 has sequence similarity to the yeast protein Prp17, which is involved in pre-mRNA splicing and cell cycle progression. The sequence similarity between the mammalian Cdc40 and the yeast Prp17 may indicate an additional role in cell cycle progression for mammalian Cdc40.
• Synonyms: CDC40; Cell division cycle 40 homolog; EH-binding protein 3; EHB3; Ehb3; hPRP17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRPF17
• Note: For research use only, not for use in diagnostic procedure.

Reference Data