Nectin 2 (NECTIN2) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:2000~1:5000 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CD112/NECTIN2. |
| Specificity | CD112/NECTIN2 polyclonal antibody detects endogenous levels of CD112/NECTIN2 protein. |
| Buffer | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
| Concentration | 1mg/ml |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 60-70 kDa |
| Gene Name | nectin cell adhesion molecule 2 |
| Database Link | |
| Background | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive .Probable cell adhesion protein . |
| Synonyms | CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin-2; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2 |
| Note | For research use only, not for use in diagnostic procedure. |
| Reference Data | |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
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