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Enpp1 Rabbit Polyclonal Antibody

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SKU
TA389625
Enpp1 Rabbit pAb
Size:
100 ul
Conjugation:
Unconjugated
  $410.00
3 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application ELISA, ICC/IF, WB
Recommended Dilution WB,1:500 - 1:1000
IF/ICC,1:50 - 1:200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 103kDa
Gene Name ectonucleotide pyrophosphatase/phosphodiesterase 1
Database Link
Background This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms M6S1; NPP1; NPPS; PC-1; PC1; PCA1; PDNP1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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