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HEXIM1 Rabbit Polyclonal Antibody

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SKU
TA384406
HEXIM1 Rabbit polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $380.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application ELISA, ICC, IHC, WB
Recommended Dilution WB:1/500-2000
IHC:1/100-300
ICC/IF:1/200-1000
ELISA:1/10000
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human HEXIM1. AA range:181-230
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Concentration lot specific
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size Observed MW (kDa):40
Gene Name hexamethylene bis-acetamide inducible 1
Database Link
Background Swiss-Prot Acc.O94992.Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:14580347, PubMed:15713661, PubMed:15201869). In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:12832472, PubMed:14580347, PubMed:15713661, PubMed:15201869). May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity (PubMed:15940264, PubMed:15941832, PubMed:17088550). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728).
Synonyms CLP-1; CLP1; EDG1; FLJ13562; HIS1; HMBA-inducible; MAQ1
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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