LIN37 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human prostate cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human LIN37 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Gene Name | lin-37 DREAM MuvB core complex component |
| Database Link | |
| Background | The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2. |
| Synonyms | Antolefinin; F25965; lin-37; MGC9505; ZK418.4 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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