GPT2 Rabbit Polyclonal Antibody

SKU
TA368451
GPT2 rabbit polyclonal antibody
  $310.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 200-1000
WB positive control: Human fetal brain tissue lysate
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human GPT2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size 58 kDa
Gene Name glutamic pyruvate transaminase (alanine aminotransferase) 2
Database Link
Background This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Synonyms ALT2
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

Roles of glutamic pyruvate transaminase 2 in reprogramming of airway epithelial lipidomic and metabolomic profiles after smoking
Yan, Zhang, Duan et al
Clin Transl Med (2024) 14 (5), e1679 DOI: 10.1002/ctm2.1679
Cited by 7
AI Summary: In this study, the OriGene anti-GPT2 antibody (TA368451) was used to detect GPT2 protein levels, enabling the researchers to investigate the role of GPT2 in airway epithelial lipid and metabolic reprogramming after smoking.
Snippet: S‐PAGE), and electrophoresed on a polyvinylidene fluoride (PVDF) membrane. Primary antibodies are as follows: GAPDH (KC‐5G4, 1:1000, KangChen Bio‐Tech, Shanghai, China), GPT2 (TA368451, 1:1000, OriGene, Beijing, China), ACLY (ab40793, 1:1000, Abcam, Cambridge, UK), DGAT1 (A6857, 1:1000, Abclonal, Wuhan, China), and anti‐mouse/rabbit HRP‐linked IgG antibodies (1:2000, #7076/#7074, Molecul
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WB
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