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DOCK11 Rabbit Polyclonal Antibody

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SKU
TA368199
DOCK11 rabbit polyclonal antibody
Size:
100 ul
Conjugation:
Unconjugated
  $310.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 20-100
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human DOCK11
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Gene Name dedicator of cytokinesis 11
Database Link
Background Small GTPases of the Rho family, Rho, Rac, and Cdc42, are critical regulators of the actin cytoskeleton and many other cellular processes. Rho GTPases are activated by Dbl-homology (DH)-domain-containing guanine nucleotide exchange factors (GEFs). DOCK 11 (dedicator of cytokinesis 11), also known as ACG or ZIZ2 (zizimin2), is a 2073 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins that is mainly expressed in peripheral blood leukocytes. DOCK 11 functions as a GEF that binds and activates Cdc42 by exchanging bound GDP for free GTP. Cdc42 mediates cell polarity, gene expression, cell cycle progression and cell–cell contacts. Similar to other DOCK family members, DOCK 11 contains a PH domain and two internal DOCK homology regions designated DHR1 and DHR2.
Synonyms ACG; bB128O4.1; FLJ32122; FLJ43653; ZIZ2; Zizimin-2; zizimin2
Reference Data
Protein Categories Cytokines, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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