BMP2 Rabbit Polyclonal Antibody

CAT#: TA367870

BMP2 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: Hela HepG2 293T cell lysates Primary antibody: TA367870 (BMP2 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA367870 (BMP2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA367870 (BMP2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA367870 (BMP2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA367870 (BMP2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hela, HepG2, 293T cell lysates
  IHC: 50-100
  Positive control: Human liver cancer
  Predicted cell location: Secreted
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human BMP2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 45 kDa
• Gene Name: bone morphogenetic protein 2
• Database Link:
  Entrez Gene 650 Human
  UniProt ID P12643
• Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
• Synonyms: BMP-2; BMP-2A; BMP2A