STEAP2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: Human stomach tissue, Human placenta tissue lysates IHC: 50-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Cell membrane |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human STEAP2 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 56 kDa |
| Gene Name | STEAP2 metalloreductase |
| Database Link | |
| Background | This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Synonyms | IPCA-1; IPCA1; OTTHUMP00000067572; OTTHUMP00000067575; PCANAP1; PUMPCn; STAMP1; STMP |
| Reference Data | |
| Protein Categories | CAR-T Targets, Intracellular Proteins, Membrane Proteins |
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