PCCB Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Mouse heart tissue, Mouse kidney tissue lysates IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human PCCB |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Shipping | Blue Ice |
Predicted Protein Size | 58 kDa |
Gene Name | propionyl-CoA carboxylase beta subunit |
Database Link | |
Background | The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | DKFZp451E113 |
Reference Data |
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