NPC2 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Mouse kidney tissue lysate IHC: 50-200 Positive control: Human tonsil Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NPC2 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Shipping | Blue Ice |
Predicted Protein Size | 17 kDa |
Gene Name | NPC intracellular cholesterol transporter 2 |
Database Link | |
Background | This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. |
Synonyms | EDDM1; HE1; MGC1333; NP-C2 |
Reference Data |
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