IFRD2 Rabbit Polyclonal Antibody

SKU
TA365849
IFRD2 rabbit polyclonal antibody
  $310.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 30-150
Positive control: Human lung cancer
Predicted cell location: Nucleus
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human IFRD2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Gene Name interferon-related developmental regulator 2
Database Link
Background IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.
Synonyms FLJ40446; IFNRP; SKMc15; SM15
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
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