UBE4A Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human UBE4A |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Gene Name | ubiquitination factor E4A |
| Database Link | |
| Background | This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Synonyms | E4; KIAA0126; MGC133315; UBOX2; UFD2 |
| Reference Data | |
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