ZNF131 Rabbit Polyclonal Antibody

SKU TA365380

ZNF131 rabbit polyclonal antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: Hela and Jurkat cell lysates，Rat brain tissue and Human testis tissue lysates; IHC: 25-100; Positive control: Human colorectal cancer; Predicted cell location: Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ZNF131
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: 71 kDa
• Gene Name: zinc finger protein 131
• Database Link:
  P52739
• Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ERå (Estrogen receptor alpha)-mediated transactivation by interrupting ERå binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events.
• Synonyms: pHZ-10

Reference Data