MAP3K9 Rabbit Polyclonal Antibody

SKU
TA364563
MAP3K9 rabbit polyclonal antibody
  $310.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-100
Positive control: Human prostate cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human MAP3K9
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Gene Name mitogen-activated protein kinase kinase kinase 9
Database Link
Background Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Synonyms MEKK9; MLK1; PRKE1
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
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