Hamp Rabbit Polyclonal Antibody
$1,270.00
2 Weeks*
Specifications
| Product Data | |
| Application | ELISA |
|---|---|
| Recommended Dilution | This antibody has been tested and validated in ELISA against Hepcidin- 25. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user. |
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Leu-Phe-Cys-Cys- Lys-Cys-Cys-Lys-Asn-Ser-Ser-Cys-Gly-Leu-Cys-Cys-Ile-Thr-OH coupled to carrier protein. |
| Buffer | Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative. |
| Reconstitution Method | Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative. |
| Concentration | N/A |
| Conjugation | Unconjugated |
| Storage | Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below. |
| Shipping | Ambient |
| Gene Name | hepcidin antimicrobial peptide |
| Database Link | |
| Background | Hepcidin-25 is a 25-residue peptide synthesized in the liver. This is the bioactive form of hepcidin, a key regulator of iron homeostasis. It acts through downregulation of the cellular iron exporter ferroportin, which is expressed on enterocytes, macrophages and hepatocytes. Hepcidin-25 production is upregulated by inflammation as well as iron overload, leading to anemia through interference with the body's intestinal iron absorption and its utilization of iron. Hepcidin is also a small defensin-like peptide with anti-microbial activity, which is secreted into the urine. This antibody was generated by immunization of rabbits with Hepcidin-25 coupled to a carrier protein. |
| Synonyms | HEPC; HEPCIDIN; HFE2; HFE2B; LEAP-1; LEAP1; PLTR |
| Reference Data | |
| Protein Categories | Growth Factors, Secreated Proteins |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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