CHMP4A Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | Expected reactivity: Cow, Human, Rabbit, Rat Homology: Cow: 77%; Human: 100%; Rabbit: 92%; Rat: 85% |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 29kDa |
| Gene Name | charged multivesicular body protein 4A |
| Database Link | |
| Background | CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression |
| Synonyms | C14orf123; CHMP4; CHMP4B; FLJ61658; hSnf-1; HSPC134; hVps32-1; MGC142093; MGC142095; SHAX2; SNF7; SNF7-1; Vps32-1; VPS32A |
| Reference Data | |
| Protein Pathways | Endocytosis |
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