Kl Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | Expected reactivity: Cow, Horse, Human, Mouse, Pig, Rabbit, Rat Homology: Cow: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 91%; Rabbit: 92%; Rat: 92% |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 116kDa |
| Gene Name | klotho |
| Database Link | |
| Background | Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1. |
| Synonyms | klotho |
| Reference Data | |
| Protein Categories | Growth Factors, Membrane Proteins, Secreated Proteins |
Reviews
Documents
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