CHAD Rabbit Polyclonal Antibody

CAT#: TA355009

Rabbit Polyclonal Anti-Chondroadherin Antibody

Product Images

Western blot analysis of Chondroadherin in 3T3 cell lysate with Chondroadherin antibody at 1ug/ml.

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  Immunocytochemistry of Chondroadherin in 3T3 cells with Chondroadherin antibody at 5ug/ml.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1-2µg/ml.IHC starting at 5µg/mL.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin.
• Formulation: Chondroadherin antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Chondroadherin antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 38 kDa; Observed: 36 kDa
• Gene Name: chondroadherin
• Database Link:
  NP_001258
  Entrez Gene 1101 Human
  UniProt ID O15335
• Background: Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5).
• Synonyms: chondroadherin; SLRR4A
• Note: Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunocytochemistry starting at 5 µg/mL.