CHAD Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | WB: 1-2µg/ml.IHC starting at 5µg/mL. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin. |
| Buffer | Chondroadherin antibody is supplied in PBS containing 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Chondroadherin antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | Predicted: 38 kDa; Observed: 36 kDa |
| Gene Name | chondroadherin |
| Database Link | |
| Background | Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5). |
| Synonyms | chondroadherin; SLRR4A |
| Note | Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Secreated Proteins |
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