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MON1B Rabbit Polyclonal Antibody

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SKU
TA354932
Rabbit anti SAND2 (Mon1b) Polyclonal Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $450.00
5 Days*
Bulk/Customize

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View other "MON1B or NM_001286639" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide derived from a portion of the intra domain 510-547aa of human Mon1b protein. This sequence is identical to human, mouse, rat, bovine and chicken.
Buffer This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 59 kDa
Gene Name MON1 homolog B, secretory trafficking associated
Database Link
Background SAND-1 (Mon1a (490aa) and Mon1b (547aa)) and CCZ-1 (Ccz1) are new factors for the apoptotic cells removal. Impaired apoptotic cell clearance (due to defective recognition, internalization or degradation) results in autoimmune disease. Mon1a and Mon1b, are similarly required for phagosome maturation. Mon1a and Mon1b are required for phagosome maturation. Mona and its partner CCZ-1 form a complex (but not either protein alone) could bind small GTPase Rab7, thus influence Rab7 activation; Mon1a, Mon1b and CCZ-1 are critical and evolutionarily conserved components regulating the processing of ingested apoptotic cell corpses.
Synonyms HSRG1; SAND2; SRG1
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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