AICDA Rabbit Polyclonal Antibody

CAT#: TA351959

Rabbit Polyclonal Anti-AICDA Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351959 (AICDA Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351959 (AICDA Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human AICDA
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: activation-induced cytidine deaminase
• Database Link:
  NP_065712
  Entrez Gene 11628 MouseEntrez Gene 57379 Human
  UniProt ID Q9GZX7
• Background: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
• Synonyms: AID; ARP2; CDA2; HEL-S-284; HIGM2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Primary immunodeficiency