TRPM6 Rabbit Polyclonal Antibody

SKU
TA351860
Rabbit Polyclonal Anti-TRPM6 Antibody
  $205.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 20-100
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human TRPM6
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name transient receptor potential cation channel subfamily M member 6
Database Link
Background This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms CHAK2; HMGX; HOMG; HOMG1; HSH
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Protein Kinase, Transmembrane
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