HUNK Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HUNK |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | hormonally up-regulated Neu-associated kinase |
| Database Link | |
| Background | The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. |
| Synonyms | hormonally up-regulated Neu-associated kinase; hormonally upregulated Neu-associated kinase; hormonally upregulated neu tumor-associated kinase; OTTHUMP00000107427; serine; threonine protein kinase MAK-V |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
Reviews
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