RNF43 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: Jurkat cells |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RNF43 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 86 kDa |
| Gene Name | ring finger protein 43 |
| Database Link | |
| Background | RNF43 (ring finger protein 43), also known as URCC or RNF124, is a 783 amino acid single-pass type I membrane protein of the Endoplasmic reticulum and nuclear envelope that is thought to function as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger and existing as four alternatively spliced isoforms, RNF43 is expressed in fetal kidney and lung, as well as in cancers of the lung, colon and kidney. RNF43 functions as a cytotoxic T lymphocyte tumor antigen, and is therefore considered a target for cancer immunotherapy. |
| Synonyms | RNF124; SSPCS; URCC |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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