PARP3 Rabbit Polyclonal Antibody

CAT#: TA351492

Rabbit Polyclonal Anti-PARP3 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human cerebrum tissue lysate Primary antibody: TA351492 (PARP3 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA351492 (PARP3 Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA351492 (PARP3 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351492 (PARP3 Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351492 (PARP3 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human cerebrum tissue lysate
  IHC: 20-100
  Positive control: Human gastric cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PARP3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: poly(ADP-ribose) polymerase family member 3
• Database Link:
  NP_005476
  Entrez Gene 10039 Human
  UniProt ID Q9Y6F1
• Background: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair