PARP4 Rabbit Polyclonal Antibody

CAT#: TA351491

Rabbit Polyclonal Anti-PARP4 Antibody

Product Images

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (PARP4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (PARP4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PARP4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: poly(ADP-ribose) polymerase family member 4
• Database Link:
  NP_006428
  Entrez Gene 143 Human
  UniProt ID Q9UKK3
• Background: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
• Synonyms: ADPRTL1; ARTD4; p193; PARP-4; PARPL; PH5P; VAULT3; VPARP; VWA5C

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair