RHEB Rabbit Polyclonal Antibody

CAT#: TA351443

Rabbit Polyclonal Anti-RHEB Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-6: Human brain malignant glioma tissue Jurkat cells Raji cells 231 cells human fetal brain tissue Hela cells Primary antibody: TA351443 (RHEB Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351443 (RHEB Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351443 (RHEB Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351443 (RHEB Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351443 (RHEB Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human brain malignant glioma tissue, Jurkat, Raji and 231 cells, human fetal brain tissue and Hela cells
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RHEB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: Ras homolog enriched in brain
• Database Link:
  NP_005605
  Entrez Gene 19744 MouseEntrez Gene 26954 RatEntrez Gene 6009 Human
  UniProt ID Q15382
• Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
• Synonyms: RHEB2

Reference Data

• Protein Pathways: Insulin signaling pathway, mTOR signaling pathway