MCC Rabbit Polyclonal Antibody

SKU TA351387

Rabbit Polyclonal Anti-MCC Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human liver cancer; Predicted cell location: Cytoplasm or Nucleus
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MCC
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: mutated in colorectal cancers
• Database Link:
  NP_002378
  P23508
• Background: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: MCC1

Reference Data

• Protein Families: Druggable Genome