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ITPR2 Rabbit Polyclonal Antibody

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SKU
TA351305
Rabbit Polyclonal Anti-ITPR2 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human ITPR2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name inositol 1,4,5-trisphosphate receptor type 2
Database Link
Background Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Synonyms CFAP48; IP3R2
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Long-term potentiation, Oocyte meiosis, Phosphatidylinositol signaling system, Vascular smooth muscle contraction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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