IL19 Rabbit Polyclonal Antibody

SKU TA351285

Rabbit Polyclonal Anti-IL19 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Raji, Hela and Jurkat cell lysates; IHC: 50-100; Positive control: Human colorectal cancer; Predicted cell location: Secreted
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human IL19
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 20 kDa
• Gene Name: interleukin 19
• Database Link:
  NP_715639
  Q9UHD0
• Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
• Synonyms: IL-10C; MDA1; NG.1; ZMDA1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway